"The molecular mechanism of action passes through the activation of the JAK/STAT pathway for virus infection resistance and activation of caspases for apoptosis induction in malignant cells. 7 to 25% of patients treated subcutaneously with IFNa-2B produce ADAs. Adverse effects reported after the treatment with IFNa-2B or PEG-IFNa-2B are flu-like symptoms occurring 1 to 3 hours after the treatment and caused by proinflammatory cytokines, induction of Systemic Lupus Erythematosus has also been reported.
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Citation: Costa SL (2014) Antiglioma Potential of Flavonoides. J Bioanal Biomed 6: e124."
Last date updated on May, 2021