Eukaryotic Inhibitors

"The effect of eukaryotic inhibitors was evaluated on growth and chitinase production of the recombinant yeast. The transcriptional inhibitors (8-hydroxyquinoline and 8-azaguanine) inhibited the growth of YT 5 significantly (< 20%) but in the presence of CHI (100 µg/ml), more than 75% was observed. The protein profile was comparatively reduced to 6% and 20% at 100 µg/ml of 8-hydroxyquinoline and 250 µg/ml of 8-azaguanine, respectively when supplemented in the culture medium. Even though relative growth and protein concentrations were reduced in the presence of transcriptional inhibitors, chitinase activity was higher by 70%. In the presence of CHI (50 µg/ml) the chitinase established 10 ± 1.06% of higher activity than the control but the growth and total protein had not been altered much by CHI. OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals with the support of 50,000+ editorial board members as editorial team and aimed to disseminate the scholarly knowledge to the scientific society. OMICS Group also organizing 3000+ International Scientific Conferences and events yearly all over the world with the support of 1000+ Scientific associations worldwide.

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Last date updated on April, 2024