"Protease is one of the most important industrial enzymes due to having some biotechnological interests. It account for about 60% of the total worldwide sale of enzymes, and is widely used in several industries that include leather processing, meat processing, dairy, preparation of organic fertilizer, silk industry, and also for the recovery of silver from used X-ray films . They catalyze important proteolytic steps in tumor invasion, or in infection cycle of a number of pathogenic microorganisms. Among all proteases, alkaline proteases are robust in nature, and are primarily used as detergent additives . Microbial proteases are produced from high yielding strains including species of Bacillus sp., Alcaligenes faecalis, Pseudomonas fluorescens and Aeromonas hydrophilia grown under submerged culture conditions. Among these, Bacillus sp. is the most important group of bacteria that are involved in the enzyme industry, and this bacterium is also known to produce proteolytic enzymes quite effectively.
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Last date updated on July, 2014