|"Among microorganisms that colonize living wood, white-rot fungi are regarded as considerable lignin degraders. They produce extracellular enzymes, such as MnP, LiP and laccase, which play important roles in lignin biodegradation. Pleurotus ostreatus is a white rot fungus belonging to the basidiomycetes and it is also considered to be a cholesterol reducing mushroom. It was also noticed that the deficiency of ligninases started in some genera of Basidiomycetes, such as Pleurotus spp., especially ligninolytic laccases involved in the degradation of lignin. The combined action of laccase and aryl alcohol oxidase decreases the molecular weights of soluble lignosulphonates secreted by P. ostreatus. Ligninolytic system configuration is complicated and species restricted. White rot fungi produce ligninases, including MnPs, LiPs and Lcc, which are possible contributors to fungal ligninolysis. White-rot fungi were mainly found to produce consistent products following the ligninolysis of model lignin compounds. MnP belongs to the family of peroxidases.