Aspirin (acetylsalicylic acid), with fewer adverse reactions than salicylic acid, was first generated as an antipyretic analgesic through acetylation of salicylic acid in the late 19th century. Since then, aspirin has long been used as an ingredient in anti-inflammatory agents worldwide and is commonly used as a drug with antiinflammatory, antipyretic and analgesic effects, as well as antiplatelet and antirheumatic effects. Aspirin has been used as a prescription drug and nonprescription (over-the-counter) drug, and demand for the drug has steadily increased. However, some nonprescription drugs that are formulated with a large amount of aspirin and no antacid have potent effects, which raise concern about the use of these products. Consequently, cases of aspirin poisoning caused by overdose are common.
A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.
Last date updated on June, 2014