Some types of cancer run in certain families, but most cancers are not clearly linked to the genes we inherit from our parents. Most cancers develop because of a combination of chance and our environment Cancer is not usually inherited, but some types mainly breast, ovarian and prostate cancer can be strongly influenced by genes and can run in families. There are two basic types of genetic mutations: acquired and germline. Acquired mutations are the most common cause of cancer. These mutations occur from damage to genes during a persons life, and they are not passed from parent to child. Tobacco use, exposure to ultraviolet (UV) radiation (such as sunlight or from tanning beds), viruses, and age can damage genes and cause these mutations. Cancer that occurs because of acquired mutations is called sporadic cancer. Many cancers cannot be linked to a specific gene. It is likely that multiple, different genes are involved in the development of cancer. There is also some evidence that genes interact with their environment, further complicating the role of genes in cancer.
Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results.
Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications.
The concept of "review article" is separate from the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it is possible for a review to be non-peer-reviewed.
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Last date updated on July, 2014