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"Thrombocytopenia is defined as a platelet count below 150×109/l, caused by accelerated platelet destruction or decreased production. It is classified as mild with a platelet count of 100-150×109/l, moderate at 50-100×109/l and severe with less than 50×109/l. Thrombocytopenia is secondly to anaemia as the most common hematologic abnormality during pregnancy. Indeed, a platelet count <150×109/l can be observed in 6 to 15% of pregnant women at the end of pregnancy. Thrombocytopenia is usually moderate (<100×109/l in only 1% of women) and often incidentally detected on routine blood count. Gestational Thrombocytopenia (GT) is considered the most prevalent cause of thrombocytopenia during pregnancy accounting for about 75% of cases. The etiology is unknown, but it is considered to be due to the relative hemodilution of pregnancy, amplified by the capture or destruction of platelets in the placenta.( Pafumi C, Valenti O, Giuffrida I, Colletta G, D’agati A, et al. (2012) Gestational Thrombocytopenia: Does it cause any Maternal and/or Perinatal Morbidity?)"
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Last date updated on April, 2021