The umbilical cord blood has been used successfully as a source of stem cells for hematopoietic reconstitution as an alternative to bone marrow or peripheral blood progenitor cells. Related and unrelated transplants of umbilical cord blood have been used for children with malignant and non-malignant diseases. Transplantation of UCB has been used with successful outcomes for the treatment of leukemia, lymphoma, myelodysplasia, aplastic anemia (AA), hemoglobinopathies, metabolic storage diseases and immunodeficiencies. Several research groups are studying the usefulness of cord blood for other hematologic diseases, in particular to repair damage caused by heart disease and stroke, diabetes mellitus, traumatic brain and spinal cord injury.
Last date updated on November, 2020