Helicobacter pylori infection is common, even in pediatric patients. The organism is the most prevalent gastric microbial pathogen. However, the major route of transmission remains poorly understood. It is currently estimated that about half of the worldâs human population is infected with H. pylori. However, the prevalence of H. pylori is not homogenous worldwide; it varies depending on the patientâs chronologic age, country of origin, ethnicity and socioeconomic background during childhood. There are vigorous innate and adaptive immune responses to H. pylori infection. Nevertheless, unless specific eradication therapy is provided, the gastric infection persists for lifetime.
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Last date updated on June, 2014