"Mesenchymal stem cells (bone mesenchymal stem cells, BMSCs), unlike hematopoietic stem cells, are present in bone marrow. BMSCs have become a progressive research field in modern biology and medicine. Mesenchymal stem cells (MSCs) are derived from the mesoderm early in development and can be exploited as an ideal source of seed cells, which exhibit the potential to be induced into osteogenic, chondrogenic, and adipogenic cells, or even tendon and adipose tissues. MSCs are easy to obtain culture and expand in vitro and can be easily induced into designated tissues. Currently, bone marrow-derived MSCs (BMSCs) are widely used. However, the amount of MSCs in bone marrow is extremely low and accounts for about 0.01~0.001% of the bone marrow derived cells. Increasing evidence indicates that MSCs with osteogenic potential can be isolated from a diverse range of tissues, including adipose tissue and perinatal tissues, such as umbilical cord, placenta, umbilical cord blood , and amniotic fluid, or even fetal blood, bone marrow, and liver.
(Xue-Guang Zhang, Fang Li, Zong-Ning Miao, Yun-Yun Xu, Shi-Ying Zheng, Ming-De Qin and Yan-Zheng Gu- Transplantation of Human Amniotic Mesenchymal in the Treatment of Focal Cerebral Ischemia)."
Last date updated on February, 2021