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Heteromorphism

We aimed to study the impact of chromosomal heteromorphisms of Acrocentric chromosomes on recurrent miscarriages in the present study, by comparing the frequencies of heteromorphic regions in Karyotypes of normal individuals and the couples with recurrent pregnancy losses. We studied and compared the chromosome Heteromorphisms in the Karyotypes of two groups. The first group consisted of 160 couples with more than two first trimester miscarriages and no live birth that were referred to our Genetic Health & Research Center between October 2010 to December 2011 for Karyotyping and the second group consisted of 412 individuals of 206 normal couples with more than 1 normal child births and absence of history of abortions. At least 20 metaphases were analysed for each case and heteromorphisms were reported according to ISCN 2005. Sandesh Chopade, Impact of Chromosomal Heteromorphisms on Recurrent Miscarriages
 
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