The effects of placental ischemia on blood pressure and many facets seen in preeclampsia can be attenuated with inhibition of T cells either by blockade of antigen presenting cells interacting with T cells or by overall T cell deficiency. Importantly, these data suggests the potential use of anti- inflammatories targeting T cell suppression as a therapeutic for preeclampsia. These studies highlight the importance of targeting CD4+ T cell suppression as an avenue to decrease blood pressure, cytokine production, anti-angiogenic factors, autoantibodies and uterine artery resistive index to improve preeclampsia symptoms late in pregnancy in PE women.
High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information.The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on October, 2020