Haematopoietic stem cell transplantation (AHSCT) is becoming a preferred treatment of unfavourable high-risk solid tumours in children. Malignant tumours that require AHSCT treatment are considered rare. These can be lymphomas or solid tumours such as neuroblastomas, Ewingas sarcomas/primitive neuroectodermal tumours (PNET), rhabdomyosarcomas, nephroblastomas, brain tumours and germ-cell tumours.
Indications for stem cell transplantation include disseminated high-risk tumours or tumours with an expected short survival using conventional treatment (expected long-term survival < 30%). AHSCT is also indicated in cases of partial response to induction therapy and disease relapse.
Here we present the results of patients who were treated for solid malignant tumours and lymphomas with high-dose chemotherapy and autologous haematopoietic stem cell transplantation as well as specific issues and solutions encountered in every-day practice in AHSCT.
A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record
Last date updated on April, 2024
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