Innate Response To Infection

The innate immune response to an infection is a first line rapid reaction consisting of two elements: recognition of invading microorganisms and complex biochemical and cellular consequences of this fact. The innate immune response has been regarded as relatively non-specific but sensitive. The cellular elements of innate immunity are represented by phagocytic cells and antigen-presenting cells-granulocytes, macrophages and dendritic cells (DCs) respectively, cytotoxic NK cells, γδ T lymphocytes. The innate immune system recognizes conserved microbial structures called pathogen-associated molecular patterns that have been implicated in activating the host innate response. These structures are sensed by germ lineencoded pattern recognition receptors (PRRs) represented by Toll-like receptors (TLRs) expressed at the cell surface or intracellularly and Nod-like receptors. The early immune reaction includes complement activation, phagocytosis and immune activation by different families of PRRs. Innate Response to Infection-Malgorzata Lipinska-Gediga OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals. Journal of Bacteriology & Parasitology is one of the top Peer-reviewed open access journals that emphasises Microbiological, diagnosis, treatment of infections with their Therapeutic & diagnostics aspects. It publishes original research articles, novel, and scientifically sound findings dealing with Bacteria and Parasites of Medical relevance to human or veterinary health, as well as those with application in Environmental or Food Sciences related to microbiology.

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Last date updated on September, 2024