Type-2 Diabetes Mellitus (T2DM) may be conceptually defined as a heterogeneous group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It is important to note however that hyperglycemia may simply represent a distal and terminal aspect of a broad series of silent, individual molecular events, involving peripheral insulin resistance, rupture of glycogen homeostasis, and relative insulin secretion response failure. It is generally accepted that T2DM is a polygenic disorder composed of subtypes whereby genetic susceptibility is strongly associated with environmental factors. Thus, this metabolic epidemic explosion represents the phenotypic expression to a collision between genes and environment.
Internal Medicine Open Access, an official journal of OMICS International publishes all the articles related to Type-2 Diabetes Mellitus. The journal is subjecting all the received manuscripts to a strict peer review process. The articles published in the journal are Open Access i.e, freely accessible to readers all around the world. Internal Medicine Open Access is maintaining the quality of articles through its strict peer review process.
Last date updated on July, 2014