Glucose is the most preferred energy substrate for brain and it is almost entirely oxidized to CO2 and H2O under normal conditions. Oxygen consumption and CO2 production in brain is almost identical thus indicating that carbohydrates are its substrates for oxidative metabolism. Glucose apart from being oxidized also enters other metabolic fates such as being incorporated into lipids, proteins and also being utilized as a precursor for certain neurotransmitters such as Î³-aminobutyric acid (GABA), glutamate or acetylcholine. neurodegenerative diseases have also been shown to affect glucose metabolism in brain. Alzheimerâs disease (AD) affected brain exhibits lower metabolic rates of glucose and abnormalities in insulin sensitivity in brain which leads to a hyperglycemic environment which possibly leads to neuronal death
Scholarly journal is a peer-reviewed journal in which scholarship relating to a particular academic discipline is published. Scholarly journals serve as forums for the introduction and presentation for scrutiny of new research, and the critique of existing research. Content typically takes the form of articles presenting original research, review articles, and book reviews.The term Scholarly journal applies to scholarly publications in all fields; this article discusses the aspects common to all academic field journals.
Last date updated on July, 2020