Spinal Cord Injury (SCI) affects approximately 10,000 people per year in North America, with a prevalence of over a million people. administration of NSC or progenitor cells could reconstitute the architecture of the injured spinal cord as well as reconnect spinal cord tracts. Marrow stromal cells (MSCs) most commonly harvested from the bone marrow, are mesenchymal stem cells because of the capacity for differentiation into tissues of mesodermal origin cells such as bone, fat, muscle, and cartilage. The use of bone-marrow derived stem cells (MSCs) has not resulted in exceptional clinical improvements, nor has its effectiveness in differentiating into NSCs and reconstituting the normal spinal cord architecture.
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Last date updated on September, 2014