alexa Epigenetic Targeting|omicsgroup|Journal Of Plant Pathology And Microbiology

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Epigenetic Targeting

How DNA methylases target genomic sequences is a poorly understood, yet vital component in growth homeostasis in mammals. One mechanism of epigenetic targeting in animals has been shown to involve homology directed repair of double strand DNA breaks. This process leaves behind a methylation scar, which is a source of selective pressure that may promote carcinogenesis. Lessons from the plant reveal that small RNAs direct DNA methylation; however, in animals, RNA based methylation targeting is not understood. A recent report that RNA gene products regulate the DNA-damage response in animal cells, makes a strong imperative for a rigorous search for RNA based targeting mechanisms in humans. OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals with the support of 50,000+ editorial board members as editorial team and aimed to disseminate the scholarly knowledge to the scientific society. OMICS Group also organizing 3000+ International Scientific Conferences and events yearly all over the world with the support of 1000+ Scientific associations worldwide. Citation: Muller MT (2012) Epigenetic Targeting in Cancer: Garden Variety Instructions? J Plant Pathol Microb 3:e103.
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Last date updated on November, 2020