Ketamine is a drug used for the induction and maintenance of general anesthesia, usually in combination with a sedative. Ketamine as an analgesic has proven to be of some effect in patients with severe pain who have failed to respond to other routinely applied pharmacotherapy. In patients with intractable pain, the use of oral ketamine can be beneficial. From this perspective, oral ketamine may be used with precautions as add-on therapy when other therapeutic options have failed. However, the routine use of ketamine in cancer pain management is still insufficiently studied. After reviewing research which uses ketamine in the management of cancer pain; further RCTs are needed to include all types of cancer to gain more knowledge about the benefits/adverse effects of using ketamine to manage cancer pain. As for recommendation for practice, we recommend the use of Palliative Care Guidelines and to take into consideration the importance of using ketamine and observing any possible side effect that may occur during or after treatment.
The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on September, 2020