Ketamine is a drug used for the induction and maintenance of general anesthesia, usually in combination with a sedative. Ketamine as an analgesic has proven to be of some effect in patients with severe pain who have failed to respond to other routinely applied pharmacotherapy. In patients with intractable pain, the use of oral ketamine can be beneficial. From this perspective, oral ketamine may be used with precautions as add-on therapy when other therapeutic options have failed. However, the routine use of ketamine in cancer pain management is still insufficiently studied. After reviewing research which uses ketamine in the management of cancer pain; further RCTs are needed to include all types of cancer to gain more knowledge about the benefits/adverse effects of using ketamine to manage cancer pain. As for recommendation for practice, we recommend the use of Palliative Care Guidelines and to take into consideration the importance of using ketamine and observing any possible side effect that may occur during or after treatment.
The top open access journals are peer reviewed scholarly journals of Journal of Pain & Relief. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in MEDLINE, PUBMED, SCOPUS, COPERNICUS, CAS, EBSCO and ISI
Last date updated on June, 2014