|Epidemiological studies and clinical trials indicate conclusively that high serum cholesterol is a major risk factor for coronary heart disease and that lowering cholesterol levels reduces the risk .The three major sizes of lipoprotein particles in which cholesterol circulates in the plasma are: very low density lipoprotein cholesterol (VLDL-C) low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C). Several large epidemiological studies suggest that for each 1 mg.dLâ1 increase in HDL-C, there is an accompanying 2% decrease in coronary heart disease risk in men and a 3% decrease in women. A low LDL-C level does not eliminate the risk impacted by a low HDL-C but a high HDL-C appears to offset some of the risk of a high LDL-C. HDL-C is the âgarbage trucksâ of the blood system, collecting cholesterol and dumping it into the liver. HDL-C plays a critical role in reverse cholesterol transport. It may retard atherogenesis by maintaining endothelial function
Journal Article is sometimes called a Scientific Article, a Peer-Reviewed Article, or a Scholarly Research Article. Together, journal articles in a particular field are often referred to as The Literature.
Journal articles are most often Primary Research Articles. However, they can also be Review Articles. These types of articles have different aims and requirements. Sometimes, an article describes a new tool or method.
Because articles in scientific journals are specific, meticulously cited and peer-reviewed, journal databases are the best place to look for information on previous research on your species. Without a background in the field, journal articles may be hard to understand - however, you do not need to understand an entire article to be able to get valuable information from it.