"Biotoxins from certain marine fishes are not only harmful to marine animals and their native environment, but also have pharmacological importance, and can be used as medicines. An investigation was carried out to study the effects of liver biotoxins of marine fish (Chelonodon patoca), catfish (Osteogeneiosus militaries), and mackerel (Rastrelliger kanagurta) on mouse, and their established kidney and liver cell lines. Among the three toxins, puffer liver toxin was the most toxic in mouse, with 5 mouse units/ml, followed by 2.5 mouse units/ml and 0.67 mouse units/ml of catfish and mackerel, respectively. The morphological rigidity, viability, swelling and syncitia formation, followed by cell death, are the common features recorded in both cell lines. The Tissue Culture Infective Dose (TCID50) was the highest for puffer liver toxin in both cell lines, followed by catfish and mackerel liver toxin.
Yogesh Kumar; Effect of Liver Biotoxins of Certain Marine Fishes on Mouse Cell Culture" Journal Article is sometimes called a Scientific Article, a Peer-Reviewed Article, or a Scholarly Research Article. Together, journal articles in a particular field are often referred to as The Literature.
Journal articles are most often Primary Research Articles. However, they can also be Review Articles. These types of articles have different aims and requirements. Sometimes, an article describes a new tool or method.
Because articles in scientific journals are specific, meticulously cited and peer-reviewed, journal databases are the best place to look for information on previous research on your species. Without a background in the field, journal articles may be hard to understand - however, you do not need to understand an entire article to be able to get valuable information from it.
Last date updated on July, 2014