Down syndrome (DS), is usually based on a two-stage model: screening tests directed at the entire population of pregnant women and invasive diagnostic tests for the high risk population as determined by the aforesaid screening tests. Screening tests include different combinations of maternal serum biochemical markers and various ultrasound markers. Currently, the most prevalent screening test is the combined first trimester screening test, which includes ultrasound measurement of nuchal translucency in combination with maternal serum levels of PAPP-A and free beta-hCG. This approach is gradually replacing second trimester biochemical screening which is based on maternal serum levels of AFP, hCG, uE3 (with or without inhibin A). Additional approaches include various combinations of first- and second-trimester screening markers, such as the integrated test and contingent screening.
Journal of Physical Medicine & Rehabilitation Open Access is one of the top online publishing journals for research from the field of Down Syndrome. The open access articles published in this scholarly journal are reviewed by at least two reviewers of the associated fields. The journal publishes original research articles, reviews, case reports, short communications, etc and emphasizes theoretical and experimental work. To ensure high quality articles, both editors and reviewers actively participate in the peer review process and help in completing the review process within 21 days. As an important educational platform the journal provides scientists and researchers access to the newest trends and research outlooks. Please browse through the list of peer-reviewed journals to find the scientific publication of your interest.
Last date updated on September, 2014