FISH was developed in early 80s and became one of the most sensitive assays for localization of specific nucleic acid sequences and detection of numerical chromosome abnormalities, structural chromosomal rearrangements and cryptic abnormalities. Bone marrow aspirate and peripheral blood smears can be used for FISH analysis. FISH makes use of fluorescent probes which hybridize only to complementary sequences and the resulting signals are examined under a fluorescent microscope. The utility of specific FISH probes provides intense signals and multiple targets can be visualized simultaneously by using probes labled with different fluorescent colors.
Journal of Medical Diagnostic Methods is one of the top online publishing journals for research from the field of Fluorescence Insitu Hybridization. The open access articles published in this scholarly journal are reviewed by at least two reviewers of the associated fields. The journal publishes original research articles, reviews, case reports, short communications, etc and emphasizes theoretical and experimental work. To ensure high quality articles, both editors and reviewers actively participate in the peer review process and help in completing the review process within 21 days. As an important educational platform the journal provides scientists and researchers access to the newest trends and research outlooks. Please browse through the list of peer-reviewed journals to find the scientific publication of your interest.
Last date updated on September, 2014