|Influenza remains a global threat and a significant public health problem. Insight into the process of influenza viral variation can help inform public health policy, antiviral drug development and protective vaccine design. We report here a bioinformatic analysis of subsets of the Hemagglutinin (HA) gene of the 2009-2010 pandemic H1N1 influenza virus. Subset sorting was based upon the HA nucleotide position of maximum information entropy (H). The sorting of HA gene mutants reported here is consistent with the non-random organization of intergenic mutual information in the pandemic virus previously reported.
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