|Sedation is an essential element in the treatment of Critical Care Units. Patients receive sedation for hours or days, mainly because of its dependence on mechanical ventilation. The sedative drugs most commonly used in these Units are intravenous hypnotic drugs generally used and recommended in the Clinical guides. However, its use in these patients poses a number of problems. On one side, the sedation level is hard to assess, intravenous sedation cannot be controlled by its plasmatic concentration, but by its effects. On the other side, there seems to be some disadvantages and serious side effects.
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