|Pseudomonas aeruginosa is the most frequently isolated bacterium among those gram negative rods that are obligate aerobes (non-fermenters). It is a major cause of nosocomial infections where the source is often contaminated IV fluids, ophthalmic solutions, hydrotherapy tanks, respiratory equipment and even disinfectant solutions such as quaternary ammonium compounds. In the absence of strict hand washing protocols, this organism may be spread from patient to patient by the hands of hospital personnel. Organisms that have colonized the host to become part of the microbiota of the respiratory and gastrointestinal tract are another important source of infection. Five - 10% of healthy individuals may carry Pseudomonas aeruginosa in their gastrointestinal tract, but that percent increases among hospitalized patients because of the selective pressure of antibiotics.
Infection with Pseudomonas aeruginosa is a major problem in immuno compromised individuals such as patients with skin and soft tissue injuries (i.e. burn victims), intravenous drug users, patients on long term, broad spectrum antibiotics, neutropenic patients, and patients with respiratory diseases, especially cystic fibrosis patients. Pseudomonas aeruginosa infections are particularly dangerous because the organism is frequently resistant to many commonly used antibiotics.
A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.