Melanin is the main pigment responsible for skin, eye, and hair color. The melanocortin 1 receptor (MC1R), a seven transmembrane G-protein coupled receptor located in the membrane of epidermal and follicular melanocytes, is a key protein involved in the regulation of melanin production (reviewed in ). Ligands of MC1R include the paracrine hormones, alpha-melanocyte stimulating hormone (ñ-MSH) and adrenocorticotropic hormone.
(Robert K. Valenzuela, Shosuke Ito, Kazumasa Wakamatsu, Murray H. Brilliant Prediction Model Validation: Normal Human Pigmentation Variation).
Evidence of clinical association of vitiligo with AID of organs like pernicious anemia, thyroid disease, IDDM
is noted. Eight subtypes are generalised, focal, acrofacial, mucosal, segmental, lip-tip, universalis, unclassified with 30% with minimal type (<2% body surface involvement), 70% extensive type (>5%). In 75% patients, cosmetic success rates observed with split-skin grafting and 35% with epidermal blister grafting which is most commonly used in north-east. 10% used punch graft followed by PUVA or topical fluocinolone acetonide found 80% repigmentation in both cases.
(Lalchamliani Khiangte, Recent clinical advances in Cosmetic treatment and management of different types of skin discoloration and depigmentation in the North-East India)
OMICS Journals refers to the Journals of OMICS Online Publishing Group are engaged in the publishing articles related to the field of genomics, proteomics, glycomics, lipidomics, transcriptomics, metabolomics and ergonomics. The aim of the OMICS Journal focuses on specific research discipline, contributing resourceful and impactful platform to embrace the developments in research with technology. OMICS International has been successful in making its spot in scientific community with 700+ peer-reviewed journals with the support of 50,000+ editorial board members, publishing more than 13000 articles in a year which are accessible to more than 100000 scholars worldwide through World Wide Web. It is also a leading scientific event organizer, organizes over 3000+ International Scientific Conferences all over the world annually with the support from 1000+ Scientific associations.
Last date updated on September, 2024
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi