Oxidative stress, defined as a disturbance in the balance between the production of reactive oxygen species (free radicals) and antioxidant defenses, is discussed in relation to its possible role in the production of tissue damage in diabetes mellitus.
Several studies have suggested that oxidative stress could play a role in the pathogenesis of nonalcoholic fatty liver disease and more precisely in the transition between simple fatty liver and steatohepatitis. Some studies have suggested that, apart from endotoxins, cytokines, hyperlipidemia and hyperinsulinemia, oxidative stress could play a role in the pathogenesis of Nonalcoholic Fatty Liver Disease (NAFLD) and more precisely in the transition between simple fatty liver and steatohepatitis (i.e. fatty liver coexistent with hepatocyte necrosis and inflammation). Indeed, excessive fat accumulation in the liver, whatever its cause, is prone to attack by Reactive Oxygen Species (ROS), leading to lipid peroxidation with its cellular consequences. For example, increased lipid peroxidation has been documented in animal models, either drug-induced or dietary while in genetic models of steatosis, such as the ob/ob mice there is an increase in mitochondrial ROS production.
Journal of Metabolic Syndrome is a Peer reviewed open access journal, which ensures the quality of published article. Each article should pass through a single blinded review process in which two independent review comments followed by Editors decision is needed to process the article further. This peer reviewed Metabolic Syndrome Journal thus gives the world class scientist a barrier free access to the research work.
Journal Article is sometimes called a Scientific Article, a Peer-Reviewed Article, or a Scholarly Research Article. Together, journal articles in a particular field are often referred to as The Literature.
Journal articles are most often Primary Research Articles. However, they can also be Review Articles. These types of articles have different aims and requirements. Sometimes, an article describes a new tool or method.
Last date updated on July, 2014