alexa Articles On Systemic Inflammation|OMICS International|Journal Of Metabolic Syndrome

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Articles On Systemic Inflammation

There appears to be a strong relationship between Metabolic Syndrome and inflammation. The type of inflammation commonly seen in patients suffering from Metabolic Syndrome is a chronic, low-rade inflammation coined systemic inflammation. Indeed, adipocytes are able to produce adipokines that may lead to a proinflammatory state. Many different adipokines are quite capable of producing systemic inflammation. However, the adipokines interleukin-6, C-reactive protein, and tumor necrosis factor alpha in particular show extensive systemic inflammation exacerbation, as these adipokines are also cytokines with acute phase and/or immune responses as their underlying purpose/operation in the body. Interleukin-6 can initiate systemic inflammation on its own as well as intensify systemic inflammation by augmenting secretion of interleukin-1 and tumor necrosis factor alpha. High levels of C-reactive protein have been linked to T2DM and CVD in addition to being a strong marker for systemic inflammation. Though it has been suggested that IR amplifies the state of proinflammation with systemic inflammation as the end outcome, there are also hypotheses supporting the notion that IR can result from systemic inflammation.
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Last date updated on July, 2014

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