alexa Microrna|omicsgroup|Molecular Biology

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Microrna

MicroRNAs (miRNAs) were originally identified in 1993, when a non-coding small RNA gene, lin-4, has been discovered in a genetic screen utilized to find out genes controlling developmental timing of the nematode, Caenorhabditis elegans larvae. Findings about lin-4 and other newly discovered small non-coding RNAs having the capacity to alter gene expression post-transcriptionally in a variety of species including mammalians, put forward miRNAs, which, are endogenously synthesized, approximately 22 nucleotide-long, single stranded and non-coding RNAs, as indispensable components of noncoding genome . Since their discovery, hundreds of miRNAs have been shown to play essential roles through modulating expression of their validated targets in several biological events both in physiological and pathological conditions and they are estimated to regulate the expression of at least 60% of human genes. In the growing environment, they are many journals in various organisations. Only a very few journals maintain high standards in terms of the content they publish, one has to be careful while picking information as content that is not reliable and untrue can be harmful to research as well as society. Generally, journals can be rated by considering impact factor, reputation of authors, editorial board members and also in terms of the fee they charge. Only high indexing journals have quality articles. Molecular Biology is one of the best journals which publish quality articles. Molecular Biology is a wide range of area that deals with different aspects. It publishes original research, review, short communication, case report, mini review etc.
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Last date updated on July, 2014

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