Indeed, one of the more recent discoveries in molecularbiology of non-coding RNAs isRNA interference (RNAi). RNAi is a method of blocking gene function by inserting short sequences of ribonucleic acid (RNA) that match part of the target genes sequence, thus no proteins are produced. Since Science named it as Breakthrough of the Year and Fortune magazine hailed it as Biotechs Billion Dollar BreakthroughÂ. RNAi is a mechanism regulating gene transcript levels by either transcriptional gene silencing (TGS) or by posttranscriptional gene silencing (PTGS), which acts in genome maintenance and the regulation of development.
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Last date updated on September, 2024