Multiple sclerosis is a chronic inflammatory, demyelinating and neurodegenerative disease of the CNS, characterized by multiple areas of white matter inflammation, demyelination, perivascular leukocyte infiltration, axonal damage and neuronal loss. Axonal loss is considered as responsible for brain and spinal atrophy and disease progression in MS patients. Neurotrophins may exert neuroprotective role in multiple sclerosis. In MS neurotrophins appear most abundantly within the actively demyelinating edge of the plaque, where they are released in close proximity of axons being at risk of damage elicited by the inflammatory reactionâ Neurotrophins and multiple sclerosis Jacek Losy and Alicja Kalinowska.
This academic open access journal aims to publish novel research and current developments in the field of multiple sclerosis neurology, multiple sclerosis rehabilitation and epidemiology of this disease progression and variations. The journal accepts articles through rapid and proper peer review process mediated through expert researchers from various countries. Apart from our editorial board members journal of multiple sclerosis also seeks the guidance and opinion from outside experts such as journal reviewers and readers. The journal highlights all the issues through our original research, review, case reports, short communications and commentaries. We believe that we are making our best efforts through this journal to highlight the recent findings and advancements regarding this inflammatory disease affecting the central nervous system.
Last date updated on January, 2021