âMultiple sclerosis (MS) is an inflammatory autoimmune disease caused due to damage to the myelin sheath covering nerve cells. Disruption of the myelin sheath results in slowing of neural transmission and causes the nerves to fatigue rapidly. The lesions are disseminated in the white matter and cause a wide range of impairments that can impact sensory, motor and/or cognitive functions. MS largely affects young adults between ages 20 and 40, Caucasians, and those who live in areas away from the equator and at high altitudes. The disease is more common in women than in men. Genetics, environmental factors and viral infections are all known to be contributing factors. However, the exact causes of MS are unknown, and there is no remedy to this disease. Common MS symptoms include weakness, fatigability, depression, spasticity, visual disturbances and parasthesias. Fatigue is one of the most bothersome symptoms in patients with MS as the disease progressesâ.
Journal of multiple sclerosis is an open access initiative in the field of multiple sclerosis research that makes free access in the field of MS research. This journal is meant for both clinicians and academic researchers working on multiple sclerosis.
Last date updated on June, 2014