|Multiple sclerosis includes an immune mediated process in which the response of the body's immune system is abnormal against the central nervous system which is made up of the brain, spinal cord and optic nerves. In this disease, the myelin sheath gets damaged, the material that surrounds and protect the nerve cells. This destruction reduced or blocks messages between the brain and the body leading to the symptoms of MS. Multiple sclerosis is also considered as autoimmune disease.
High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.