Multiple sclerosis is one of the major neurological disorders affecting central nervous system and thus causing imbalance in physical as well as mental systems. Multiple Sclerosis (MS) as other well recognized immunologically mediated diseases have a strong female predominance. Endocrine and immunological aspects are relevant where estrogens specifically estriol at a high dose, similar to that of a normal pregnancy has been shown to decrease the volume and number of gadolinium-enhancing lesions in female brains, though side effects overcome its benefits. Special considerations have to be made when referring to treatment options due to more severe side effects of disease modifying agents in women. Physiological conditions known to increase relapse rates, the post-partum period, need to be carefully evaluated when considering treatment options. MS impact over quality of life and other psychosocial issues must be meticulously studied and cared for as are the rest of the MS in women previously outlined Multiple Sclerosis in women: Pregnancy, Teresa corona.
This newly started journal on multiple sclerosis discusses the complicated physiological aspects of this disease and its impact on the quality of life. We are trying to make a timely update of research findings in this disease through our editorials, research and review articles whereas our short communications and commentaries are mainly focussed on the controversies in the field of multiple sclerosis.
Last date updated on June, 2014