âMS pathogenesis involves both inflammation and neurodegeneration. Inflammation is more common in relapsing-remitting form of MS compared to primary-progressive form of MS and, in the past, was considered a primary feature of demyelination in MS. Surprisingly, myelin destruction has recently been reported to occur before inflammation at least in some patients. It is believed that MS occurs as a result of a complex combination of genetic background and environmental factors. Studies show MS prevalence approximately 1 per 100,000 in certain areas of China, Japan and India, and approximately 10 per 100,000 in Africa, whereas numbers in Europe, Canada, and the United States are much higher. For example, MS prevalence is 248 per 100,000 in Saskatoon, a city in central Saskatchewan, Canada. In contrast to African Americans, Asian Americans continue to have low MS prevalenceâ. Balashov KE., Multiple Sclerosis: New Hypotheses Are Needed.
Journal of multiple sclerosis is a journal completely devoted to this neurological disease causing inflammation in central nervous system. The journal supports the researchers all over the world throughout their research interventions and thus helps them to reveal their findings thorough our articles.
Last date updated on July, 2014