Multiple sclerosis (MS) is an autoimmune disease, chronic disease that affects the central nervous system. MS is thought to affect the bodyâs immune system produces cells and proteins (antibodies) thus destroying the myelin and causing demylination. The destruction of fatty substance that protects nerve fibres can thus cause fatal symptoms. The major symptoms of multiple sclerosis involves gastric and bowel problems, vision problems, stiffness to muscles etc. The actual cause of this fatal disease is still is unknown.
Infectious organisms, most likely viruses, have long been a suspect for triggering the autoimmune response in people genetically susceptible to MS. Although many infectious microorganisms have been investigated, no particular organism has emerged as a proven trigger The AIDS virus is a neurotropic virus and CNS involvement as the presenting complaint is seen in approximately ten percent of cases of HIV infection. The mechanisms of demyelination in HIV infection could be due to lesions directly related to infections of the nervous system by HIV itself, opportunistic infections and lymphomas, secondary to cell mediated immunodeficiency, and other general and systemic complications of HIV Sardar P et al., Multiple Sclerosis like Demyelination in Early HIV Infection-A Rare Presentation": Case Report and Literature Review.
Last date updated on February, 2021