|Progressive Multifocal Leukoencephalopathy is a rare disease caused by JC virus infection and thus loss of myelin. Progressive multifocal leukoencephalopathy (PML) is a disorder of the central nervous system caused by the JC virus. The JC virus, a human polyoma virus, is found widespread over the globe. This disease is very closely related to multiple sclerosis. The disease causes one specific lesion in the brain. PML is often considered as a fatal disease of the central nervous system most commonly associated with severe immunodeficiency syndrome.
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