Multiple sclerosis (MS) is defined as a probable autoimmune disease that severely affects the central nervous system (CNS), resulting in several pathologies that may be a result of different disease-causing mechanisms. It is classically characterised by extensive demyelination, which is associated with perivascular leukocyte infiltration in the active lesions and inflammation in the brain and spinal cord, gliosis and axonal damage or loss. It is considered to be the main cause of non-traumatic primary neurological disability in young adults, affecting approximately 1:1000 individuals in Europe and North America with specific epidemiological âhot-spotsâ. Microglial Mechanisms Governing Axonal Degeneration in Multiple Sclerosis: A Pathological Perspective, Alrehaili A, Lee JY, Taghian K, MahaBakhurayasah, Thomas S, Petratos S.
Journal of Multiple Sclerosis is a newly started open access journal highlighting the major issues on multiple sclerosis including clinical aspects of multiple sclerosis, multiple sclerosis and rehabilitation, epidemiology and genetics of multiple sclerosis. Apart from other journals based on neurological disoders, journal of multiple sclerosis specifically deals with this autoimmune neurological disorder. This journal is supported by key research, and highly affiliated academic neurologist from various countries. The journal publishes research, review articles along with videos and images on multiple sclerosis cases and treatment.
Last date updated on June, 2014