The term Muscle contraction is defined as the stretching or relaxation of the muscle fibers. There are two kinds of Muscle contraction named voluntary and involuntary. Voluntary muscle contraction is controlled by the central nervous system. Involuntary muscle contraction is controlled by the innate or involuntary brain activity or stimuli. Two important proteins actin and myosin play vital role in the energy dependent function of the muscle. Action potential originating in CNS by calcium signaling releases acetylcholine this in turn drives the actin, myosin functions by ATP. Calcium binds to TroponinC present on the actin making it to unblocking the binding sites. Myosin binds to the unblocked binding sites on the thin filament of actin. The conversion of ADP to ATP results in the power stroke. Actin acts as a cofactor advancing the release. This results in dragging the Z-bands towards each other and shortening the I-band. Repetition of these cycles results in muscle contraction or release.
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Last date updated on June, 2014