Tuberculous Brain Abscess

Tuberculous brain abscess is a condition distinct from CNS tuberculoma. In developing countries tuberculous abscesses have been reported in 4% to 7.5% of patients with CNS tuberculosis. The histopathological diagnosis of tuberculous brain abscess depends on the following criteria: microscopic evidence of pus in the abscess cavity, microscopic changes in the abscess wall, and isolation of M tuberculosis. Abscesses are usually solitary and larger and progress much more rapidly than tuberculomas. CT and MRI pictures of a tuberculous abscess show a granuloma with a liquid centre, however, they are much larger and frequently multiloculated and with marked surrounding oedema. Clinical features include partial seizures, focal neurological deficit, and raised intracranial tension.

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Last date updated on April, 2024