To date, various nanodrug systems have been developed for different routes of administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles. Nanodrug systems have been employed to improve the efficacy, safety, physicochemical properties, and pharmacokinetic/pharmacodynamic profile of pharmaceutical substances. In particular, functionalized nanodrug systems can offer enhanced bioavailability of orally taken drugs, prolonged half-life of injected drugs (by reducing immunogenicity), and targeted delivery to specific tissues. Thus, nanodrug systems might lower the frequency of administration while providing maximized pharmacological effects and minimized systemic side effects, possibly leading to better therapeutic compliance and clinical outcomes. In spite of these attractive pharmacokinetic advantages, recent attention has been drawn to the toxic potential of nanodrugs since they often exhibit in vitro and in vivo cytotoxicity, oxidative stress, inflammation, and genotoxicity. A better understanding of the pharmacokinetic and safety characteristics of nanodrugs and the limitations of each delivery option is necessary for the further development of efficacious nanodrugs with high therapeutic potential and a wide safety margin.
The articles related to nano drugs are published in journals of OMICS International, which are of high impact factor .These articles are of high quality standards and have numerous citations .These articles is peer reviewed by eminent editorial members . OMICS Group international is an Open Access publisher that publishes about 700+ peer-reviewed journals on a variety of subjects with the team of above 25000 editorial board members. It organizes over 3000+ International Scientific Conferences. The quality manuscripts related to nano drugs is available in OMICS journal of Nano medicine and bio therapeutic discovery.
Last date updated on September, 2014