"Journal of Lasers, Optics & Photonics is one of the open access journals in lasers and optics. The open access policy of the journals aims at increasing the visibility and accessibility of the published content and thus providing the desirable researches to the readers.
The biomedical applications of plasmonic nanoparticles (NPs) use their optical scattering properties for imaging and diagnostics and their photothermal properties for various types of therapies through the generation of heat, vapor bubbles and acoustic waves. The specificity and sensitivity of imaging and diagnostics as well as the selectivity and efficacy of the therapeutic methods depend upon the selectivity of NP delivery and activation within their targets, typically diseased cells or tissues. The initial application of various NPs was based on passive targeting, which did not allow the NPs to recognize their specific molecular targets and resulted in the low selectivity of NP-based methods and also in potentially toxic loads of NPs. The situation was improved by using active molecular targeting with cell-specific molecules (peptides, antibodies, aptamers) attached to NPs and coupling to cognate receptors at the membranes of specific target (diseased) cells.
Title:Rainbow Plasmonic Nanobubbles: Synergistic Activation of Gold Nanoparticle Clusters
Author:Dmitri O Lapotko
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Last date updated on June, 2014