Alkaloids are naturally occurring chemical compounds containing basic nitrogen atoms. The name derives from the word alkaline is due to nitrogen containing base. Alkaloids are produced by a large variety of organisms, including bacteria, fungi, plants, and animals and are part of the group of natural products, also called secondary metabolites. Many alkaloids are purified from crude extracts by acid-base extraction. Many alkaloids are toxic to other organisms. They often have pharmacological effects and are used as medications, as recreational drugs, or in entheogenic rituals. Examples are the local anesthetic and stimulant cocaine, the stimulant caffeine, nicotine, the analgesic morphine, or the antimalarial drug quinine. Some alkaloids have a bitter taste. The classification of the alkaloids is complex and is by a set of rules like structure and other chemical features of the alkaloid molecule, its biological origin, as well as the biogenetic origin where known. The groups are Pyridine group, Pyrrolidine group, Tropane group, Indolizidine group, Quinoline group, Isoquinoline group, Phenanthrene alkaloids, Phenethylamine group, Indole group: Purine group and terpenoid group
Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results.
Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications.
The concept of ""review article"" is separate from the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it is possible for a review to be non-peer-reviewed.
Last date updated on September, 2014