Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Nuclear Localization Signal

APE1 is a central enzyme of BER-pathway with primary two major independent cellular functions; repair and redox. Both functions are displayed by two different regions of the protein. Primarily, repair function through C-terminus, which involves removal of AP sites in DNA. Second function is reductive activation of several TFs displayed via disordered N-terminus which also possesses the Nuclear Localization Signal (NLS), controlling gene expression for significant cellular pathways. Because of redox activity, APE1 is also known as redox effector factor-1. OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals with the support of 50,000+ editorial board members as editorial team and aimed to disseminate the scholarly knowledge to the scientific society.
  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger

Last date updated on September, 2024

Top