|Osteosarcoma is a highly malignant tumor with extensively destructive potential. It is also the most common primary malignant injury of bone. It is a true cancerous degeneration of bone, which establishes itself in the form of a white or reddish mass, lardaceous and firm at an early stage of the disease; but at a later period, presenting with points of softening, cerebriform matter, extravasating blood, and white or straw colored fluid of a viscid consistence in its interior.
High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.