|Oropharyngeal is a cancer related to mouth and food tract where cells turn malignant. It is of two types i.e hpv positive and human papillomavirus. The symptoms include sore throat, voice modulation, ear pain etc. it can be treated by combing chemotherapy and radiotherapy. The risk factors causing disease are smoking, alcohol, chewing betel nut, poor nutrition etc. Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results. Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications.The concept of "review article" is separate from the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it is possible for a review to be non-peer-reviewed.