Bone is a living tissue that undergoes continuous remodeling, a process which depends on bone resorption by osteoclasts on the one hand and bone formation by osteoblasts on the other. These mechanisms are tightly coupled in space and time. Measurements of specific, circulating markers of bone resorption and formation, respectively released by osteoclasts and osteoblasts, reflect the overall timing of bone turnover and help defining the balance between these competing constituents of bone metabolism.
Peer review refers to the work done during the screening of submitted manuscripts and funding applications. This process encourages authors to meet the accepted standards of their discipline and reduces the dissemination of irrelevant findings, unwarranted claims, unacceptable interpretations, and personal views. Publications that have not undergone peer review are likely to be regarded with suspicion by academic scholars and professionals.
Last date updated on September, 2014