|"The reduced and the reversibly oxidized cysteine in the single sample for monitoring the cysteine modifications alternative to ICAT reagent approach, C ysTRAQ combines iTRAQ with a PTM peptide enrichment method to identify and quantify cysteine-containing peptides. This approach was further modified a tandem chemical labeling approach, in which both iTRAQ and thebiotinylated thiol-reactive reagents were applied to label the reversibly oxidized cysteine-containing peptides, and named as OxiTRAQ.
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Citation: Hu Q, Guo G, Yang Z, Li Y, Xia Y (2014) Stable Isotope Metabolic Labeling-Based Quantitative Thiol Redox Proteomic Analysis of Hydrogen Peroxide-treated Arabidopsis plant. J Proteomics Bioinform 7: 121-133."